Synthesis of Dihydroindolo[2,3-c]carbazole as Potential Telomerase Inhibitor artículo Académico uri icon

abstracto

  • The dictyodendrins A-E were the first marine natural products that show inhibition of telomerase. A versatile and convergent route was described for the synthesis of derivatives of these pyrrolo[2,3-c]carbazole alkaloids as potential inhibitors of telomerase, by cyclotrimerization [2 + 2 + 2] of ruthenium-catalyzed diynamides diarylacetylenes. © 2015 HeteroCorporation.

fecha de publicación

  • 2016